ジャガイモデンプンから調製したリン酸化オリゴ糖のラットのカルシウム吸収に及ぼす影響

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  • Effect of Phosphorylated Oligosaccharide from Potato-starch on Calcium Absorption in Rats.
  • ジャガイモ デンプン カラ チョウセイシタ リンサンカ オリゴトウ ノ ラット

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Previously, we observed the inhibitory effect of phosphorylated oligosaccharides (PO) from potatostarch on the formation of calcium phosphate precipitate. PO were composed of two fractions: PO-1 and PO-2. The former was maltooligosaccharide bound to one phosphate molecule, and the latter was maltooligosaccharide bound to at least two phosphate molecules. PO-2 had a stronger inhibitory effect. In the present study, we investigated the effect of PO-2 feeding on calcium utilization in rats. Five-week-old rats were fed a calcium diet (0.52% of calcium) containing 5% PO-2 for two weeks. The apparent calcium absorption ratio and apparent retention ratio during two periods (days 3-6, days 10-14) were significantly lower in the rats fed the PO-2 diet than in those fed the control diet. The results of a breaking-force test and the calcium content of the femur did not differ significantly between the two groups. Whole cecal weight was significantly higher in the rats fed the PO-2 diet, and the amounts of short-chain fatty acid in the cecal content were significantly increased; cecal pH was not changed. There was no apparent correlation between the calcium-solubilizing effect of PO-2 in vitro and the degree of calcium absorption in vivo.

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