-
- KAWAKAMI Misako
- Department of Food Science, Mukogawa Women's University
-
- KANAZAWA Kazuki
- Department of Agricultural Chemistry, Kobe University
-
- DOI Hiroshi
- Department of Food Science, Mukogawa Women's University
Bibliographic Information
- Other Title
-
- チェーブリンからの微小管形成に及ぼすレシチン過酸化物の影響
- チューブリン カラ ノ ビショウカン ケイセイ ニ オヨボス レシチン カサン
Search this article
Description
The effect of lipid peroxides on microtubule assembly was investigated. Microtubule formation from bovine brain tubulin was inhibited dosedependently by lipid hydroperoxides produced from commercial lecithin by photooxidation. This indicates the possibility of in vivo interaction of tubulin with lipid peroxides. Thus, it is possible that this interaction may be a cause of some brain diseases, based on observations of the cytoskeleton in Alzheimer's disease, and the hypothesis that the microtubule system is damaged in this disease.
Journal
-
- Nippon Eiyo Shokuryo Gakkaishi
-
Nippon Eiyo Shokuryo Gakkaishi 46 (1), 89-91, 1993
Japan Society of Nutrition and Food Science
- Tweet
Details 詳細情報について
-
- CRID
- 1390282681270158336
-
- NII Article ID
- 130000853590
-
- NII Book ID
- AN00311992
-
- ISSN
- 18832849
- 02873516
-
- NDL BIB ID
- 3815139
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed