書誌事項
- タイトル別名
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- Effects of a Diet Containing Salacia reticulata on Mild Type 2 Diabetes in Humans. A Placebo-controlled, Cross-over Trial.
- Salacia reticulata ミズ チュウシュツブツ ニ オケル キョウカイガタ オヨビ ケイショウ 2ガタ トウニョウビョウ ショウレイ ニ タイスル リンショウ コウカ
- A Placebo-controlled, Cross-over Trial
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抄録
Salacia reticulata is a plant widely known in Sri Lanka to be effective for the prevention of hyperglycemia. It has been shown that an aqueous extract from the stem of Salacia reticulata (SRE) has an inhibitory effect on alpha glucosidase activity and can thereby suppress postprandial hyperglycemia in humans. In this study, a placebo-controlled, cross-over trial was performed to evaluate the clinical usefulness of SRE for prevention or treatment of type 2 diabetes. The study subjects were 20 individuals (10 males and 10 females, average age 58.0±15.5yr) with type 2 diabetes. All revealed fasting hyperglycemia but were not on drug therapy. The subjects were divided into two groups, each of which was kept for six weeks on a SRE-containing diet (240mg/day) and a control-diet (placebo), respectively. After 6 weeks, the groups were crossed over, and another set of examinations was performed. Blood samples were obtained for laboratory examination before and after each set. The results indicated that the SRE-containing diet group achieved significant reductions in fasting plasma glucose levels, HbA1C and BMI. In contrast, no changes were observed in the control-diet group. During the trial, no severe side effects of the diet were observed in either group. Thus our present findings suggest the usefulness of a SRE diet for the health care of individuals with mild type 2 diabetes.
収録刊行物
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- 日本栄養・食糧学会誌
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日本栄養・食糧学会誌 53 (5), 199-205, 2000
公益社団法人 日本栄養・食糧学会
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詳細情報 詳細情報について
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- CRID
- 1390282681270407552
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- NII論文ID
- 10009714753
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- NII書誌ID
- AN00311992
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- ISSN
- 18832849
- 02873516
- http://id.crossref.org/issn/02873516
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- NDL書誌ID
- 5545099
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可