Effects of Intake of Fish Rich in n-3 Polyunsaturated Fatty Acid on Serum Lipids, Serum Fatty Acid Component and Hemostatic Factors.
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- Umemura Utako
- Department of Domestic Science, Tokyo Bunka Junior College
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- Ishimori Mako
- Department of Domestic Science, Tokyo Bunka Junior College
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- Watanabe Sayuri
- Department of Domestic Science, Tokyo Bunka Junior College
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- Iso Hiroyasu
- Institute of Community Medicine, University of Tsukuba
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- Shimamoto Takashi
- Institute of Community Medicine, University of Tsukuba
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- Koike Kazuko A.
- Ibaraki Prefectural University of Health Sciences
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- Kobayashi Toshio
- Fukushima Medical University
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- Iida Minoru
- The Center for Adult Diseases
Bibliographic Information
- Other Title
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- n‐3系多価不飽和脂肪酸の多い魚の摂取が血清脂質,血清脂肪酸,凝固線溶系因子に及ぼす影響
- n 3ケイ タカ フホウワ シボウサン ノ オオイ サカナ ノ セッシュ ガ ケッセイ シシツ ケッセイ シボウサン ギョウコセン ヨウケイ インシ ニ オヨボス エイキョウ
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Abstract
To examine the effects of intake of dark-meat fish (rich in n-3 polyunsaturated fatty acids) on cardiovascular disease risk factors, we conducted a trial using female college students in Tokyo. The students were randomized into a dark-meat fish intake group (intervention group, n=39) and a control group (n=35). The intervention group ate a piece or a serving of dark-meat fish as their lunch for 2 weeks, with a daily average fish intake of 80-100g. Effects of fish intake were evaluated by examining changes in serum lipids (total cholesterol, HDL-cholesterol and triglycerides) and serum fatty acid components and hemostatic factors [plasma fibrinogen, tissue plasminogen activator (t-PA), plasminogen activator inhibitor 1 (PAI-1)]. In the intervention group, after two weeks of fish intake, serum saturated fatty acid components did not change. Monounsaturated fatty acid components decreased from 24.2% to 22.1%, and polyunsaturated fatty acid components increased from 50.0% to 51.2%. In particular, n-3 polyunsaturated fatty acid components increased significantly from 6.8% to 9.7%, and the n-3/n-6 ratio increased significantly from 0.16 to 0.24. In the control group, no changes were observed in serum fatty acid components. In the intervention group, serum HDL-cholesterol increased significantly from 66 to 69mg/dL, and triglyceride tended to decrease from 66 to 58mg/dL. Serum total cholesterol did not change. No changes in serum lipid were observed in the control group. Plasma fibrinogen, t-PA or PAI-1 did not change in either the intervention group or the control group. It is concluded that a daily intake of 80-100g dark-meat fish increases serum n-3 polyunsaturated fatty acids and HDL-cholesterol.
Journal
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- Nippon Eiyo Shokuryo Gakkaishi
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Nippon Eiyo Shokuryo Gakkaishi 53 (1), 1-9, 2000
Japan Society of Nutrition and Food Science
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Keywords
Details 詳細情報について
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- CRID
- 1390282681270499712
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- NII Article ID
- 10009714205
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- NII Book ID
- AN00311992
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- COI
- 1:CAS:528:DC%2BD3cXhsVSksrY%3D
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- ISSN
- 18832849
- 02873516
- http://id.crossref.org/issn/02873516
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- NDL BIB ID
- 5280551
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed