Evidence for Stimulation of Thyroidal Secretion by Iodoaminoacids or Iodide

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  • YOSHIMURA SHIZUKO
    Division of Endocrinology and Endocrine Research Laboratory, Toranomon Hospital
  • SHISHIBA YOSHIMASA
    Division of Endocrinology and Endocrine Research Laboratory, Toranomon Hospital
  • SHIMIZU TAEKO
    Division of Endocrinology and Endocrine Research Laboratory, Toranomon Hospital

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  • Evidence for stimulation of thyroidal secretion by iodoaminoacids or iodide(Rapid communication)

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Iodoaminoacids or iodide, in a dose containing 50μg iodine stimulated intracellular colloid droplet formation and radioactive iodothyronine release in mouse prepared for McKenzie bioassay. Theophyllin enhanced those effects on both aspects. Those results may explain thyroglobulin-induced enhancement of thyroidal secretion currently drawing attention of many investigators.

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