Two Cases of Pseudoaldosteronism (Liddle's Syndrome) in Siblings

  • OHNO FUMITOSHI
    Department of Internal Medicine, School of Medicine, Tokushima University
  • HARADA HIDEO
    Department of Internal Medicine, School of Medicine, Tokushima University
  • KOMATSU KOICHI
    Department of Internal Medicine, School of Medicine, Tokushima University
  • SAIJO KAZUO
    Department of Internal Medicine, School of Medicine, Tokushima University
  • MIYOSHI KAZUO
    Department of Internal Medicine, School of Medicine, Tokushima University

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Other Title
  • Two cases of pseudoaldosteronism (Liddle′s syndrome) in siblings (Note)
  • Two cases of pseudoaldosteronism Liddle

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Description

Two cases of Liddle's syndrome were found in a brother and sister. Both showed typical hypokalemic hypertension without hyperaldosteronism. These cases showed similar responses in various pharmacological tests and their symptoms of hypokalemia and hypertention were relieved by triamterene. And in a family survey, the father appeared to be affected. This seems to be the first report on this syndrome in Japan.

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