Clinical prognostic index for recurrence of papillary thyroid carcinoma including intraoperative findings

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  • Kim Kwang Min
    Department of Surgery, The Armed Forces Capital Hospital, Korea
  • Park Joon Beom
    Department of Surgery, Wonju College of Medicine, Yonsei University, Wonju, Korea
  • Bae Keum Seok
    Department of Surgery, Wonju College of Medicine, Yonsei University, Wonju, Korea
  • Kim Chun Bae
    Department of Preventive Medicine, Wonju College of Medicine, Yonsei University, Wonju, Korea
  • Kang Dae Ryong
    Graduate School of Public Health, Yonsei University, Seoul, Korea
  • Kang Seong Joon
    Department of Surgery, Wonju College of Medicine, Yonsei University, Wonju, Korea

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抄録

This study created a new staging system using a risk model that employed clinical factors that were associated with recurrence, verified by preoperative clinical information and intraoperative finding and was compared with other staging systems. A review was conducted of patients who have undergone thyroidectomy and followed-up between January 1, 1983 and September 31, 2007 at Yonsei University Wonju Christian Hospital. The final prognostic staging system was defined as University of Yonsei clinical staging system (Prognostic score = 0.03 × Age + 0.8 × (if male gender) + 0.5 × (if extrathyroidal tumor extension present) + 0.7 × (if clinically apparent lymph node metastasis present), Stage I, less than 1.50; Stage II, 1.50 to 2.29; Stage III, 2.30 to 3.29; Stage IV 4, 3.3 or more). Compared with the other staging systems, the proportion of variation explained (PVE %) was calculated for each. The University of Yonsei clinical staging system appeared to be first as an accurate prognosis predictor with 11.9%. New staging system can predict recurrence and has advantage can use preoperative clinical information and intraoperative finding. Those who are diagnosed as high risk patients using the new staging system should be treated with aggressive surgical treatment and close follow-up.

収録刊行物

  • Endocrine Journal

    Endocrine Journal 60 (3), 291-297, 2013

    一般社団法人 日本内分泌学会

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