A screening test to detect HGH-antibodies in pituitary dwarfs treated with HGH preparation by the radioimmunoassay with double antibody technique.
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- OKADA YOSHIAKI
- Department of Medicine and Geriatrics, Osaka University Medical School
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- TAKAHASHI TATSUO
- Yodogawa Christian Hospital
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- KUMAHARA YUICHI
- Department of Medicine and Geriatrics, Osaka University Medical School
Bibliographic Information
- Other Title
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- A Screening Test to Detect HGH-Antibodies in Pituitary Dwarfs Treated with HGH Preparation by the Radioimmunoassay with Double Antibody Technique(Note)
- Screening Test to Detect HGH Antibodies
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Abstract
Sixty-four blood samples, obtained from 25 pituitary dwarfs treated with KABIHGH preparation, were checked for serum HGH concentration by a double antibody radioimmunoassay and for antibodies against HGH by the method of propylethyleneglycol separation. Antibodies to HGH were detected in the samples whose HGH concentration was falsely estimated to be more than 5ng/ml, but not in those whose HGH concentration was 5ng/ml or less. The measurement of HGH concentration by a double antibody technique in the serum obtained from pituitary dwarfs 3-4 days after the last injection can be used to screen the presence of antibodies to HGH preparation used.
Journal
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- Endocrinologia Japonica
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Endocrinologia Japonica 24 (6), 589-593, 1977
The Japan Endocrine Society
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Keywords
Details 詳細情報について
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- CRID
- 1390282681276572288
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- NII Article ID
- 130000954878
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- NII Book ID
- AA00635052
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- ISSN
- 21856370
- 00137219
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- NDL BIB ID
- 1916952
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- PubMed
- 606547
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed