Hyperaldosteronism due to Adrenocortical Adenoma and Adenomatous Hyperplasia

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  • OMAE TERUO
    Second Department of Internal Medicine Faculty of Medicine, Kyushu University
  • KAWASAKI TERUKAZU
    Second Department of Internal Medicine Faculty of Medicine, Kyushu University
  • TANAKA KENZO
    Department of Pathology Faculty of Medicine, Kyushu University
  • ARAKAWA KIKUO
    Cardiovacular Institute Faculty of Medicine, Kyushu University
  • EMOTO KANICHI
    Department of Urology Faculty of Medicine, Kyushu University
  • MASAKI JENJIRO
    Department of Urology Faculty of Medicine, Kyushu University
  • KATSUKI SHIBANOSUKE
    Second Department of Internal Medicine Faculty of Medicine, Kyushu University

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Clinical features in relation to adrenocortical pathology were described in 9 cases with primary aldosteronism with the following conclusion.<BR>When an adenoma was defined as a benign tumor being completely encapsulated, single adenoma was found in 2 cases and adenomatous hyperplasia in 7 cases. Clinical characteristics were indistinguishable between the cases with adenoma and adenomatous hyperplasia. A complete remission of the syndrome occurred in all cases following unilateral adrenalectomy. There was no marked hypoaldosteronism occurring after the surgery. Histological findings of the adrenocortical tissues surrounding adenoma or adenomatous hyperplasia and in the contralateral adrenal gland were of diffuse or micronodular hyperplasia.

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