HYPERTROPHIC CRANIAL PACHYMENINGITIS IN MPO-ANCA-RELATED VASCULITIS: A CASE REPORT AND LITERATURE REVIEW
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- WATANABE KIMIO
- Department of Internal Medicine, Division of Nephrology, Hypertension, Endocrinology, and Diabetology/Metabolism, Fukushima Medical University School of Medicine
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- TANI YOSHIHIRO
- Department of Internal Medicine, Division of Nephrology, Hypertension, Endocrinology, and Diabetology/Metabolism, Fukushima Medical University School of Medicine
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- KIMURA HIROSHI
- Department of Internal Medicine, Division of Nephrology, Hypertension, Endocrinology, and Diabetology/Metabolism, Fukushima Medical University School of Medicine
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- ASAI JUN
- Department of Internal Medicine, Division of Nephrology, Hypertension, Endocrinology, and Diabetology/Metabolism, Fukushima Medical University School of Medicine
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- TANAKA KENICHI
- Department of Internal Medicine, Division of Nephrology, Hypertension, Endocrinology, and Diabetology/Metabolism, Fukushima Medical University School of Medicine
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- HAYASHI YOSHIMITSU
- Department of Internal Medicine, Division of Nephrology, Hypertension, Endocrinology, and Diabetology/Metabolism, Fukushima Medical University School of Medicine
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- ASAHI KOICHI
- Department of Internal Medicine, Division of Nephrology, Hypertension, Endocrinology, and Diabetology/Metabolism, Fukushima Medical University School of Medicine
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- NAKAYAMA MASAAKI
- Department of Internal Medicine, Division of Nephrology, Hypertension, Endocrinology, and Diabetology/Metabolism, Fukushima Medical University School of Medicine
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- WATANABE TSUYOSHI
- Department of Internal Medicine, Division of Nephrology, Hypertension, Endocrinology, and Diabetology/Metabolism, Fukushima Medical University School of Medicine
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Abstract
A 75-year-old woman presented with rapidly progressive glomerulonephritis with positive results for anti-myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA). Corticosteroid therapy was successfully introduced. However, 7 months later, magnetic resonance imaging revealed marked swelling in the falx cerebri and high density regions were apparent on gallium scintigraphy, leading to diagnosis of hypertrophic cranial pachymeningitis (HCP). Symptoms improved with intensified corticosteroid therapy, but radiological examination 9 months later revealed right nasal sinus inflammation accompanied by osteolytic change. Granulomatosis with polyangiitis (Wegener's) was finally diagnosed. HCP is an important complication in MPO-ANCA-related vasculitis, and needs to be considered during the clinical course.
Journal
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- FUKUSHIMA JOURNAL OF MEDICAL SCIENCE
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FUKUSHIMA JOURNAL OF MEDICAL SCIENCE 59 (1), 56-62, 2013
THE FUKUSHIMA SOCIETY OF MEDICAL SCIENCE
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Details
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- CRID
- 1390282681280908032
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- NII Article ID
- 130003376088
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- NII Book ID
- AA0065246X
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- COI
- 1:STN:280:DC%2BC3sjpvVeitg%3D%3D
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- ISSN
- 21854610
- 00162590
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- PubMed
- 23842516
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- Text Lang
- en
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- Data Source
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- JaLC
- IRDB
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed