TACTILE SENSOR IS USEFUL FOR ESTIMATING LIVER HARDNESS AND LIVER FIBROSIS COMPARED WITH ULTRASONOGRAPHY AND COMPUTED TOMOGRAPHY
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- SUZUKI SATOSHI
- Department of Organ Regulatory Surgery, Fukushima Medical University
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- WATANABE YOHEI
- Department of Organ Regulatory Surgery, Fukushima Medical University
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- YAZAWA TAKASHI
- Department of Organ Regulatory Surgery, Fukushima Medical University
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- ISHIGAME TERUHIDE
- Department of Organ Regulatory Surgery, Fukushima Medical University
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- SASSA MOTOKI
- Department of Organ Regulatory Surgery, Fukushima Medical University
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- MONMA TOMOYUKI
- Department of Organ Regulatory Surgery, Fukushima Medical University
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- TAKAWA TADASHI
- Department of Organ Regulatory Surgery, Fukushima Medical University
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- KUMAMOTO KENSUKE
- Department of Organ Regulatory Surgery, Fukushima Medical University
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- NAKAMURA IZUMI
- Department of Organ Regulatory Surgery, Fukushima Medical University
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- OHOKI SHINJI
- Department of Organ Regulatory Surgery, Fukushima Medical University
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- HATAKEYAMA YUICHI
- Japan Community Health care Organization Nihonmatsu Hospital
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- SAKUMA HIROSHI
- Masu Memorial Hospital
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- ONO TOSHIYUKI
- Masu Memorial Hospital
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- OMATA SADAO
- Department of Electrical and Electronic Engineering, College of Engineering, Nihon University
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- TAKENOSHITA SEIICHI
- Department of Organ Regulatory Surgery, Fukushima Medical University
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Background/Aims: We examined whether conventional ultrasonography (US) and computed tomography (CT) were useful to evaluate liver hardness and hepatic fibrosis by comparing the results with those obtained by a tactile sensor using rats with liver fibrosis.<br>Methodology: We used 44 Wistar rats in which liver fibrosis was induced by intraperitoneal administration of thioacetamide. The CT and US values of each liver were measured before laparotomy. After laparotomy, a tactile sensor was used to measure liver hardness. We prepared Azan stained sections of each excised liver specimen and calculated the degree of liver fibrosis (HFI: hepatic fibrosis index) by computed color image analysis.<br>Results: The stiffness values and HFI showed a positive correlation (r=0.690, p<0.001), as did the tactile values and HFI (r=0.709, p<0.001).<br>In addition, the stiffness and tactile values correlated positively with each other (r=0.814, p<0.001). There was no correlation between the CT values and HFI, as well as no correlation between the US values and HFI.<br>Conclusion: We confirmed that it was difficult to evaluate liver hardness and HFI by CT or US examination, and considered that, at present, a tactile sensor is useful method for evaluating HFI.
収録刊行物
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- 福島医学会
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福島医学会 60 (2), 116-122, 2014
福島医学会
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詳細情報 詳細情報について
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- CRID
- 1390282681282666752
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- NII論文ID
- 120005620332
- 130004697214
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- NII書誌ID
- AA0065246X
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- ISSN
- 21854610
- 00162590
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- PubMed
- 25283979
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 使用不可