水溶液プロセスを用いた鉄添加ハイドロキシアパタイトの合成

  • 佐藤 充孝
    東北大学金属材料研究所附属研究施設大阪センター
  • 中平 敦
    東北大学金属材料研究所附属研究施設大阪センター 大阪府立大学

書誌事項

タイトル別名
  • Synthesis of Fe Doped Hydroxyapatite by Aqueous Solution Process
  • スイヨウエキ プロセス オ モチイタ テツ テンカ ハイドロキシアパタイト ノ ゴウセイ

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抄録

Development of non toxic magnetic beads has been strongly desired to cure more effectively for patients having diseases such as cancer and osteosarcoma. In this study, Fe doped calcium phosphate powders were prepared by aqueous solution process. The crystal phase of obtained samples had a hydroxyapatite (HAp)-related structure with low crystallinity, and the crystallinity of samples decreased with increasing ratio of Fe (RFe). The crystallinity of samples improved by heat treatment more than 1073 K for 2 hours and α-Fe2O3 phase was generated as a second phase. The lattice parameter of HAp phase drastically changed at RFe=1 mol% caused by the difference of ion radius between Ca ion and Fe ion, and there was a trend of that the a-axis shrinks and c-axis expands by further increment of RFe. The obtained powders had granular crystals with 10 nm in diameter. All samples showed paramagnetic property, and the maximum magnetization was 3×10-2 emu/g at RFe=5 mol%.

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