Hyperkalemia in extremely premature infants. Glucose-insulin therapy.

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  • 超未熟児の高Ｋ血症　ＧＩ療法
  • —GLUCOSE-INSULIN THERAPY—
  • ―GI療法―

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One of the most severe and fatal complications in extremely premature infants (ELBW) is hyperkalemia. The hyperkalemia in ELBW is caused by three factors as follows:<br>1) premature function of the kidney<br>2) catabolic states in metabolism<br>3) hypokalemia in muscle cells<br>Especially in these factors, the hypokalemia in muscle cells has a most important roll in ELBW. Birth asphyxia makes ELBW severe hyperkalemia. While it is low grade hyperkalemia yet, we can see the marked ECG changes in ELBW compared to children or adults.<br>The most effective and reasonable therapy of hyperkalemia in ELBW is glucose-insulin therapy. (G. I, therapy)<br>This is our protocol to hyperkalemia in ELBW.<br>1) Severe type; Insulin i. m. (1-2 U) +DIV (add 1 U insulin to 100 ml 10% glucose)<br>2) Mild type; DIV only 3) Preventive therapy; DIV (add 0.5 U insulin to 100 ml 1096 glucose)

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