ON THE MAINTENANCE THERAPY FOR MALIGNANT LYMPHOMA IN REMISSION

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  • 悪性リンパしゅの維持療法について
  • アクセイ リンパシュ ノ イジ リョウホウ ニ ツイテ

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Comparative studies between palliative chemotherapy, intermittent consolidation therapy and immunotherapy in 12 cases with malignant lymphoma in remission, were performed.<br>In the palliative chemotherapy, small doses of L-asparaginase with argimate to prevent side effect were most efficacy in some chemical drugs, L-asp., chlorambucil, cyclophosph-amide, procarbazine, 6MP, thiouracil and 5FU.<br>As to immunotherapy, small doses of OK432 sincrease and activate T cell. Cepha-rantin elevates immunoglobulin level and stimulates the function of RES. Transfer factor brought positive PPD reaction in negative patients.<br>It was suggested that immunotherapy prolonged remmission period but did not reduce tumor proliferation so much. The purpose of immunotherapy is the raise of the immune function in these patients and the protection from infection as well as maintenance of remission

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