Adrenalin・Predonisolone投与による末梢血液成分の変動

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書誌事項

タイトル別名
  • STUDY ON THE CHANGE OF BLOOD PICTURE DUE TO ADMINISTRATION OF ADRENALIN AND PREDONISOLONE
  • Adrenalin Predonisolone トウヨ ニ ヨル マッショウ ケツエキ セイブン ノ ヘンドウ トクニ ヒ ノ キノウ ト ノ カンレンセイ
  • —ESPECIALLY ON THE RELATIONSHIP WITH THE PRESENCE OF THE SPLEEN—
  • ―特に脾の機能との関連性―

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説明

It has been reported that administration of adrenalin or predonisolone may cause change of peripheral blood corpuscle, mainly, increase and decrease of lymphocytes, and at the same time contraction of the spleen was clinically observed.<br>The patients with various diseases concerning splenomegaly were given 1 ml of 1, 000 ×adrenalin I.M, and also given 0.5 mg/kg body weight of predonisolone I.V, and the change of blood picture was examined with the lapse of time over 120 minutes after administration. Results obtained are as follows:<br>1) In comparison of essential hypochromic anemia and hemorrhagic anemia, the former showed larger change of blood picture than the latter.<br>2) The results obtained after splenectomy in the cases with Banti's disease and idiopathic thrombocytopenic purpura were similar to these in aplastic anemia.<br>3) In three cases with splenomegaly and decrease of total blood corpuscle, changes of blood picture before splenectomy were smaller in advanced liver cirrhosis, while blood corpuscle after splenectomy were clearly decreased.<br>From the above results, it can be concluded that the change of peripheral blood corpuscle were influenced by the presence of the spleen, especially by morbid state of the spleen with hyperf unction.

収録刊行物

  • 医療

    医療 28 (6), 472-478, 1974

    一般社団法人 国立医療学会

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