Systemic Therapy for Anovulatory Sterile Women

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  • 不妊外来における排卵障害の治療方針
  • フニン ガイライ ニ オケル ハイラン ショウガイ ノ チリョウ ホウシン

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Sterile women with suspected ovarian dysfunction were tentatively classified on the basis of the BBT and the periodicity of menstruation, and a systemic treatment was applied for the induction of ovulation in each group.<br>This paper presents some results which have been obtained in our clinic from Dec. 1970 to Nov. 1972.<br>Reliable BBT were obtained with 622 cases, of which 65.5% belonged to regular diphase-eumenorrhea, and 18.0% to low monophase: the latter is seldom associated with spontaneous ovulation.<br>The Kaufmann therapy was performed in 29 cases (one course for each case), and the rebound phenomenon was noted in 9 cases, of which 4 became pregnant. A total of 387 cycles of clomiphene were administered to 109 cases, and 34 became pregnant.<br>The HMG-HCG therapy was applied to 24 cases, in which the clomiphene therapy had previously been ineffective. Ovulation were noted in 12 cases, 3 became pregnant during the administration, and additional 4 pregnancies were found in half a year. Of the whole pregnancies found within the two year observation period, about 40% were considered to be the effective cases for our ovulation-induction therapy

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