チンパンジーとハンセン病

DOI 参考文献39件

書誌事項

タイトル別名
  • Leprosy in a chimpanzee
公開日
2011
資源種別
journal article
DOI
  • 10.5025/hansen.80.29
公開者
日本ハンセン病学会

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説明

Leprosy is suspected to develop after a long period of latency following infection with Mycobacterium leprae (M. leprae) during infancy, but definitive proof has been lacking. We found a rare case of leprosy in a chimpanzee (Pan troglodytes) born in West Africa (Sierra Leone) and brought to Japan around 2 years of age. At 31, the ape started exhibiting pathognomic signs of leprosy. Pathological diagnosis, skin smear, serum anti-phenolic glycolipid-I (PGL-I) antibody, and by PCR analysis demonstrated lepromatous leprosy. Single-nucleotide polymorphism (SNP) analysis verified the West African origin of the bacilli. This occurrence suggests the possibility of leprosy being endemic among wild chimpanzees in West Africa, potentially posing a zoonotic risk.

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詳細情報 詳細情報について

  • CRID
    1390282681297776256
  • NII論文ID
    10027809196
  • NII書誌ID
    AN10559906
  • DOI
    10.5025/hansen.80.29
  • COI
    1:STN:280:DC%2BC3M3mvFaisQ%3D%3D
  • ISSN
    1884314X
    13423681
  • Web Site
    https://search.jamas.or.jp/link/ui/2011141573
  • 本文言語コード
    ja
  • 資料種別
    journal article
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
    • KAKEN
    • IRDB
  • 抄録ライセンスフラグ
    使用不可

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