書誌事項
- タイトル別名
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- Leprosy in a chimpanzee
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説明
Leprosy is suspected to develop after a long period of latency following infection with Mycobacterium leprae (M. leprae) during infancy, but definitive proof has been lacking. We found a rare case of leprosy in a chimpanzee (Pan troglodytes) born in West Africa (Sierra Leone) and brought to Japan around 2 years of age. At 31, the ape started exhibiting pathognomic signs of leprosy. Pathological diagnosis, skin smear, serum anti-phenolic glycolipid-I (PGL-I) antibody, and by PCR analysis demonstrated lepromatous leprosy. Single-nucleotide polymorphism (SNP) analysis verified the West African origin of the bacilli. This occurrence suggests the possibility of leprosy being endemic among wild chimpanzees in West Africa, potentially posing a zoonotic risk.
収録刊行物
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- 日本ハンセン病学会雑誌
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日本ハンセン病学会雑誌 80 (1), 29-36, 2011
日本ハンセン病学会
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詳細情報 詳細情報について
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- CRID
- 1390282681297776256
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- NII論文ID
- 10027809196
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- NII書誌ID
- AN10559906
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- COI
- 1:STN:280:DC%2BC3M3mvFaisQ%3D%3D
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- ISSN
- 1884314X
- 13423681
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可