Lipoprotein and Apoprotein Profiles of Hyperlipidemic Atherosclerosis-Prone Japanese Quail.
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- NAGATA Junichi
- Laboratory of Applied Biochemistry, Faculty fo Agriculture, and Clinical Laboratory Department, University of the Ryukyus
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- MAEDA Goki
- Laboratory of Applied Biochemistry, Faculty fo Agriculture, and Clinical Laboratory Department, University of the Ryukyus
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- OKU Hirosuke
- Laboratory of Applied Biochemistry, Faculty fo Agriculture, and Clinical Laboratory Department, University of the Ryukyus
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- TODA Takayoshi
- Laboratory of Applied Biochemistry, Faculty fo Agriculture, and Clinical Laboratory Department, University of the Ryukyus
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- CHINEN Isao
- Laboratory of Applied Biochemistry, Faculty fo Agriculture, and Clinical Laboratory Department, University of the Ryukyus
書誌事項
- タイトル別名
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- Lipoprotein and Apoprotein Profiles of
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抄録
The purpose of this study was to characterize the lipopro-tein and apoprotein profiles of hyperlipidemic atherosclerosis-prone (HAP) Japanese quail. HAP and commercially available (CA) Japanese quail were fed either a semi-purified diet containing 1% cholesterol or a cholesterol-free diet for two weeks. The lipoproteins of CA and HAP quail fed cholesterol-free diet were composed of two fractions: densities ranging from 1.02 to 1.09 and from 1.09 to 1.21. The lipoprotein distri-bution patterns obtained from both strains showed an HDL-predominant pattern. A protein of 26 kDa was the major apoprotein in the entire density range of the lipoprotein class. Marked increases in the cholesterol ester levels were observed in the lower density fractions (1.006<d<1.055: chylomicron and VLDL fractions) of the cholesterol-fed quail, accounting for 46% of the total lipids in CA quail and 54% in HAP quail. In addition, the presence of a protein of 470 kDa was exclusively observed in the lower density fractions (1.006<d<1.055) of the cholesterol-fed HAP quail. The fatty-acid compositions of the chylomicron and VLDL fractions were affected by the dietary cholesterol in both strains: a decrease in concentration of 16:0 and increase in 18:0 (weight%). However, cholesterol feeding had no effect on the level of cholesterol, chemical composition or fatty-acid composition of the HDL fractions in either strain. Although the lipoprotein and apoprotein profiles of HAP quail showed resemblances to those of the CA quail, expression of the 470 kDa protein in the lipoproteins (d<1.055) appeared to be pronounced in HAP quail. The relevance of these lipoprotein and apoprotein profiles to the genesis of atherosclerosis was discussed in this study.
収録刊行物
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- Journal of Nutritional Science and Vitaminology
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Journal of Nutritional Science and Vitaminology 43 (1), 47-57, 1997
一般財団法人 学会誌刊行センター
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詳細情報 詳細情報について
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- CRID
- 1390282681299040128
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- NII論文ID
- 130001370224
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- NII書誌ID
- AA00703822
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- COI
- 1:CAS:528:DyaK2sXivVWqtro%3D
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- ISSN
- 18817742
- 03014800
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- NDL書誌ID
- 4176341
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- PubMed
- 9151240
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可