Beneficial Effect of a Low Dose of Ethanol on Liver Function and Serum Urate in Rats Fed a High-Fat Diet
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- OSAKI Aimi
- Graduate School of Biosphere Science, Hiroshima University
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- OKAZAKI Yukako
- Faculty of Human Life Sciences, Fuji Women’s University
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- KIMOTO Akiko
- Graduate School of Biosphere Science, Hiroshima University
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- IZU Hanae
- National Research Institute of Brewing
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- KATO Norihisa
- Graduate School of Biosphere Science, Hiroshima University
Bibliographic Information
- Other Title
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- Beneficial effect of low dose of ethanol on liver function and serum urate in rats fed a high-fat diet
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Description
This study investigated the effects of the consumption of 1% or 2% (v/v) ethanol in drinking water for 12 wk on rats fed a high-fat diet. Body weight gain, food intake, and fluid intake were unaffected by ethanol intake. Adipose tissue weight, and serum glucose and lipids were unaffected. Compared to the control (no ethanol), 1% ethanol intake significantly reduced serum levels of alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and ammonia (p<0.05), whereas 2% ethanol intake did so to a lesser extent. Serum urate was significantly lower in both the 1% and 2% ethanol groups than that in the control group (p<0.05). The results suggest a low dose of ethanol has beneficial effects on liver function and serum urate in rats fed a high-fat diet.
Journal
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- Journal of Nutritional Science and Vitaminology
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Journal of Nutritional Science and Vitaminology 60 (6), 408-412, 2014
Center for Academic Publications Japan
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Details 詳細情報について
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- CRID
- 1390282681300747648
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- NII Article ID
- 130005060918
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- NII Book ID
- AA00703822
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- ISSN
- 18817742
- 03014800
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- NDL BIB ID
- 026007966
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- PubMed
- 25866304
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- NDL Search
- Crossref
- PubMed
- CiNii Articles
- KAKEN
- OpenAIRE
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- Abstract License Flag
- Disallowed
