Beneficial effect of low dose of ethanol on liver function and serum urate in rats fed a high-fat diet
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- OSAKI Aimi
- Graduate School of Biosphere Science, Hiroshima University
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- OKAZAKI Yukako
- Faculty of Human Life Sciences, Fuji Women’s University
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- KIMOTO Akiko
- Graduate School of Biosphere Science, Hiroshima University
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- IZU Hanae
- National Research Institute of Brewing
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- KATO Norihisa
- Graduate School of Biosphere Science, Hiroshima University
書誌事項
- タイトル別名
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- Beneficial Effect of a Low Dose of Ethanol on Liver Function and Serum Urate in Rats Fed a High-Fat Diet
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説明
This study investigated the effects of the consumption of 1% or 2% (v/v) ethanol in drinking water for 12 wk on rats fed a high-fat diet. Body weight gain, food intake, and fluid intake were unaffected by ethanol intake. Adipose tissue weight, and serum glucose and lipids were unaffected. Compared to the control (no ethanol), 1% ethanol intake significantly reduced serum levels of alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and ammonia (p<0.05), whereas 2% ethanol intake did so to a lesser extent. Serum urate was significantly lower in both the 1% and 2% ethanol groups than that in the control group (p<0.05). The results suggest a low dose of ethanol has beneficial effects on liver function and serum urate in rats fed a high-fat diet.
収録刊行物
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- Journal of Nutritional Science and Vitaminology
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Journal of Nutritional Science and Vitaminology 60 (6), 408-412, 2014
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詳細情報 詳細情報について
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- CRID
- 1390282681300747648
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- NII論文ID
- 130005060918
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- NII書誌ID
- AA00703822
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- ISSN
- 18817742
- 03014800
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- NDL書誌ID
- 026007966
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- PubMed
- 25866304
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可