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Antidiabetic Effects of Ajoene in Genetically Diabetic KK-Ay Mice
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- HATTORI Atsuhiko
- BiodeveIopment Division, Central Institute, Nagoya Seiraku Co. Ltd.
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- YAMADA Norihiko
- BiodeveIopment Division, Central Institute, Nagoya Seiraku Co. Ltd.
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- NISHIKAWA Tomoaki
- BiodeveIopment Division, Central Institute, Nagoya Seiraku Co. Ltd.
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- FUKUDA Hiroyuki
- BiodeveIopment Division, Central Institute, Nagoya Seiraku Co. Ltd.
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- FUJINO Tsuchiyoshi
- BiodeveIopment Division, Central Institute, Nagoya Seiraku Co. Ltd.
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Description
Antidiabetic effects of ajoene, derived from garlic, were investigated in genetically diabetic KK-Ay mice. Four-week-old male KK-Ay mice were kept on a laboratory diet containing 0.02 or 0.05% of ajoene for 8 wk. The elevation of water intake was suppressed depending on ajoene intake. The levels of plasma glucose in the 0.05% ajoene-containing diet group was significantly suppressed to 73.8% compared with the control group at the 8th wk. Similarly, the plasma triglyceride level was significantly suppressed. It is suggested that hyperglycemia and hypertriglyceridemia are suppressed by ajoene treatment.
Journal
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- Journal of Nutritional Science and Vitaminology
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Journal of Nutritional Science and Vitaminology 51 (5), 382-384, 2005
Center for Academic Publications Japan
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Details 詳細情報について
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- CRID
- 1390282681300952064
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- NII Article ID
- 110002704092
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- NII Book ID
- AA00703822
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- ISSN
- 18817742
- 03014800
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- NDL BIB ID
- 7681184
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL Search
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed