Effect of Active Hexosc Correlated Compound (AHCC) in Alcohol-Induced Liver Enzyme Elevation
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- KIM Hyangkyoung
- Department of Surgery, Chung-Ang University Healthcare System, Chung-Ang University College of Medicine
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- KIM Jung-Ha
- Department of Family Medicine, Chung-Ang University Healthcare System, Chung-Ang University College of Medicine
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- IM Jee-Aee
- Sports and Medicine Research Center, INTOTO Inc.
書誌事項
- タイトル別名
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- Effect of Active Hexose Correlated Compound (AHCC) in Alcohol-Induced Liver Enzyme Elevation
- 公開日
- 2014
- 資源種別
- journal article
- DOI
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- 10.3177/jnsv.60.348
- 公開者
- 一般財団法人 学会誌刊行センター
この論文をさがす
説明
To investigate the effects of Active Hexose Correlated Compound (AHCC) supplementation and the mechanism action of AHCC in patients with alcohol-induced mildly elevated liver enzyme levels, participants were randomly allocated to the placebo, 1 g AHCC, or 3 g AHCC group and took the supplement for 12 wk. Subjects visited the hospital for clinical and biochemical measurements, for examination of adverse events, to return unused supplements, and to obtain their next supplements. Biochemical tests including liver enzymes, a questionnaire survey, and anthropometric measurements were collected at baseline and every 4 wk thereafter. Adherence and adverse events were evaluated. After 12 wk of supplementation, the percentage change in alanine aminotransferase (ALT) level was significantly different between the placebo (4.02±59.07%) and both AHCC groups (1 g AHCC: 223.89±20.59%, 3 g AHCC: 224.09±30.73%) (p=0.04). Serum levels of tumor necrosis factor-α (p<0.05) and interleukin-1β (p<0.01) were significantly lower, while those of adiponectin were higher in both AHCC groups than in the placebo group (p<0.01). AHCC supplementation for 12 wk may improve the levels of liver enzymes and circulating pro-inflammatory and anti-inflammatory cytokines in patients with alcohol-induced liver enzyme elevation with mildly elevated liver enzyme levels.
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ｎｕｔｒｉｔｉｏｎａｌ Ｓｃｉｅｎｃｅ ａｎｄ Ｖｉｔａｍｉｎｏｌｏｇｙ
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Ｊｏｕｒｎａｌ ｏｆ Ｎｕｔｒｉｔｉｏｎａｌ Ｓｃｉｅｎｃｅ ａｎｄ Ｖｉｔａｍｉｎｏｌｏｇｙ 60 (5), 348-356, 2014
一般財団法人 学会誌刊行センター
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詳細情報 詳細情報について
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- CRID
- 1390282681301358336
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- NII論文ID
- 130004773629
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- NII書誌ID
- AA00703822
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- ISSN
- 18817742
- 03014800
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- NDL書誌ID
- 025880706
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- PubMed
- 25744424
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- PubMed
- CiNii Articles
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