Ultrastructure of platelets of the vitamin E-deficient rats.

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  • 有森 茂
    Fourth Department of Internal Medicine, School of Medicine, Tokai University
  • 住友 和代
    Fourth Department of Internal Medicine, School of Medicine, Tokai University

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  • Ultrastructure of Platelets of the Vita

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The platelets of vitamin E-deficient rats show a remarkable structural destruction of the mitochondria, mainly in the membrane, and a considerable decrease in the number of mitochondria. In addition, signi-ficant decreases are manifested in the numbers of microtubules, α-granulomers, dense bodies and glycogen particles, accompanied by re-markable vacuole formation.<br> The longer the vitamin E-deficient period, the more remarkable the changes are. Rats deficient in vitamin E for 58 weeks showed the highest degenerative changes in the platelets.

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