Utilization of N-acetyl-L-tryptophan given intravenously to unrestrained adult rats.

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  • 藤田 美明
    Nutrition Research Laboratory, Tokyo Metropolitan Institute of Gerontology
  • 安西 正弘
    Department of Nutrition, School of Medicine, Tokushima University
  • 乾 政子
    Department of Nutrition, School of Medicine, Tokushima University
  • 西本 隆子
    Department of Nutrition, School of Medicine, Tokushima University
  • 井上 五郎
    Department of Nutrition, School of Medicine, Tokushima University

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  • Utilization of N Acetyl L Tryptophan Gi

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The nutritional value of N-acetyl-L-tryptophan (NALT) given intravenously was examined in unrestrained adult rats. They were given solutions of 4% Vuj pattern amino acids, 24.5% glucose, vitamins and electrolytes intravenously for 10 days. They were divided into three groups; one group was then injected intravenously with complete amino acid solution (T group), one with tryptophan-free amino acid solution (TF group) and one group with complete amino acid solution but with NALT instead of tryptophan (NALT).<br> The biological value of the NALT group was 49.6; this value corresponded to 90% of that of the T group. Excretion of injected amino acids totalled about 2.0 to 3.0% in this experiment. The effects of NALT on carcass composition, certain blood constituents and tryptophan pyrrolase activity in the liver were also examined.

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