Ovarian Localization of Immunoglobulin G and Inhibin α-Subunit in Guinea Pigs after Passive Immunization against the Inhibin α-Subunit
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- SHI FangXiong
- Department of Basic Veterinary Sciences, The United Graduate School of Veterinary Sciences, Gifu University Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology College of Animal Sciences, Zhejiang University
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- MOCHIDA Keiji
- Department of Veterinary Science, National Institute of Infectious Diseases
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- SUZUKI Osamu
- Department of Veterinary Science, National Institute of Infectious Diseases
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- MATSUDA Junichiro
- Department of Veterinary Science, National Institute of Infectious Diseases
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- OGURA Atsuo
- Department of Veterinary Science, National Institute of Infectious Diseases
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- OZAWA Manao
- Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology
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- WATANABE Gen
- Department of Basic Veterinary Sciences, The United Graduate School of Veterinary Sciences, Gifu University Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology
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- SUZUKI Akira K.
- Air Pollutants Health Effects Research Team, National Institute for Environmental Studies
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- TAYA Kazuyoshi
- Department of Basic Veterinary Sciences, The United Graduate School of Veterinary Sciences, Gifu University Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology
書誌事項
- タイトル別名
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- Ovarian Localization of Immunoglobulin G and Inhibin .ALPHA.-Subunit in Guinea Pigs after Passive Immunization against the Inhibin .ALPHA.-Subunit.
- Ovarian Localization of Immunoglobulin G and Inhibin アルファ Subunit in Guinea Pigs after Passive Immunization against the Inhibin アルファ Subunit
この論文をさがす
抄録
The experiment was conducted to elucidate ovarian localization of immunoglobulin G (Ig G) and inhibin α-subunit and follicular development in guinea pigs after passive immunization against the inhibin α-subunit. Estrus was synchronized in laboratory guinea pigs by implanting progesterone containing-tubes. After removal of the progesterone implants, the guinea pigs were injected i.v. with 1.0 ml inhibin antiserum or normal goat serum (NGS). The results showed that Ig G mainly entered the follicular fluid of antral follicles, indicating that possibly inhibin antibodies could be a local regulator affecting follicular development in guinea pigs. The results also showed that passive immunization against inhibin increased the number of follicles and plasma concentrations of estradiol before ovulation, but did not change the plasma concentrations of follicle-stimulating hormone (FSH) or the numbers of follicles stained with inhibin antiserum. The present study first reports that the distribution of Ig G after injections of inhibin antiserum and confirms our previous hypothesis that only dominant follicles could be stained for inhibin α-subunit. The results also imply that only one injection of inhibin antiserum could not increase the ovulation rate in guinea pigs.
収録刊行物
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- Journal of Reproduction and Development
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Journal of Reproduction and Development 46 (5), 293-299, 2000
公益社団法人 日本繁殖生物学会
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詳細情報 詳細情報について
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- CRID
- 1390282681310315776
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- NII論文ID
- 10027321214
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- NII書誌ID
- AA10936678
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- COI
- 1:CAS:528:DC%2BD3MXktFKjtw%3D%3D
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- ISSN
- 13484400
- 09168818
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- NDL書誌ID
- 5560723
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可