片側および両側を潜伏精巣にした成熟ラットにおける生殖ホルモン濃度と精巣中インヒビン含量について

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  • Reproductive hormone levels and testicular inhibin content in adult rats after the unilateral and bilateral cryptorchidism.
  • 片側および両側を潜伏精巣にした成熟ラットにおける生殖ホルモン濃度と精巣中インヒビン含量について〔英文〕
  • カタガワ オヨビ リョウガワ オ センプク セイソウ ニ シタ セイジュク ラ

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Reproductive hormone levels and testicular inhibin content in adult rats after theexperimental unilateral and bilateral cryptorchidism were investigated. The weight of abdominally placed testis decreased by about 40% of control testis 2 weeks after surgery. There were no changes in seminal vesicle weight. The cryptorchidism groups exhibited a significant increase in serum FSH levels. In contrast, serum LH level in the unilateral group showed no significant difference from control, while increased significantly in the bilateral group. The levels of serum testosterone in the bilateral group decreased, but not in the unilateral one. The contents of testosterone in the unilateral cryptorchid rats decreased in the abdominal testis and increased in the scrotal. In the bilateral cryptorchid rats, there were no changes in testicular testosterone content. Inhibin contents in the abdominal testis of both unilateral and bilateral cryptorchid rats were significantly lower than control. These results suggest that there is no compensatory function concerning the inhibin synthesis in Sertoli cells, unlike the testosterone production in Leydig cells in the intact testis following unilateral cryptorchidism.

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