Zygotic Gene Activation and Maternal Factors in Mammals
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- MINAMI Naojiro
- Laboratory of Reproductive Biology, Graduate School of Agriculture, Kyoto University
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- SUZUKI Toru
- Laboratory of Reproductive Biology, Graduate School of Agriculture, Kyoto University
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- TSUKAMOTO Satoshi
- Laboratory of Reproductive Biology, Graduate School of Agriculture, Kyoto University
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抄録
Zygotic gene activation (ZGA) is the first event of gene expression after fertilization. Following fertilization, ZGA occurs within a short time interval depending on the animal species. Until ZGA, maternal proteins and transcripts stored in oocytes control embryonic development, indicating the importance of maternal factors for development. Somatic cell cloning also proves the potential of oocyte to reprogram the differentiated cell nuclei to embryonic nuclei. Recent studies show that the epigenetic modifications of nuclei play important roles in controlling gene expression during ZGA. However, the mechanisms that control ZGA remain largely unknown. This review will cover the current understanding of ZGA. Specifically, it will focus on the maternal factors that control gene expression during early embryogenesis.<br>
収録刊行物
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- Journal of Reproduction and Development
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Journal of Reproduction and Development 53 (4), 707-715, 2007
公益社団法人 日本繁殖生物学会
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詳細情報 詳細情報について
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- CRID
- 1390282681313859840
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- NII論文ID
- 10020003415
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- NII書誌ID
- AA10936678
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- COI
- 1:CAS:528:DC%2BD2sXhtFGgs7fI
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- ISSN
- 13484400
- 09168818
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- NDL書誌ID
- 8882629
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- PubMed
- 17827882
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可