Factors Affecting the Development of Somatic Cell Nuclear Transfer Embryos in Cattle
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- AKAGI Satoshi
- Animal Breeding and Reproduction Research Division, NARO Institute of Livestock and Grassland Science, Ibaraki 305-0901, Japan
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- MATSUKAWA Kazutsugu
- Multidisciplinary Science Cluster, Life and Environmental Medicine Science Unit, Kochi University, Kochi 783-8502, Japan
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- TAKAHASHI Seiya
- Headquarters, National Agriculture and Food Research Organization, Ibaraki 305-8517, Japan
Bibliographic Information
- Other Title
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- SRD Outstanding Research Award 2013 : Factors Affecting the Development of Somatic Cell Nuclear Transfer Embryos in Cattle
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Abstract
Nuclear transfer is a complex multistep procedure that includes oocyte maturation, cell cycle synchronization of donor cells, enucleation, cell fusion, oocyte activation and embryo culture. Therefore, many factors are believed to contribute to the success of embryo development following nuclear transfer. Numerous attempts to improve cloning efficiency have been conducted since the birth of the first sheep by somatic cell nuclear transfer. However, the efficiency of somatic cell cloning has remained low, and applications have been limited. In this review, we discuss some of the factors that affect the developmental ability of somatic cell nuclear transfer embryos in cattle.
Journal
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- Journal of Reproduction and Development
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Journal of Reproduction and Development 60 (5), 329-335, 2014
The Society for Reproduction and Development
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Details 詳細情報について
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- CRID
- 1390282681314233344
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- NII Article ID
- 130004700241
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- NII Book ID
- AA10936678
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- COI
- 1:STN:280:DC%2BC2M3jtVKltQ%3D%3D
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- ISSN
- 13484400
- 09168818
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- NDL BIB ID
- 025861757
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- PubMed
- 25341701
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed