STRUCTURAL CHANGES OF THE RAT CHOROID PLEXUS FOLLOWING INTRAVENTRICULAR INJECTION OF SOME DRUGS

DOI オープンアクセス

書誌事項

タイトル別名
  • TRANSMISSION AND SCANNING ELECTRON MICROSCOPIC OBSERVATION

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説明

Ultrastructures of the choroid epithelium of the rats were examined by means of transmission and scanning electron microscopy after intraventricular injection of pilocarpine and puromycin. In the rats to which isotonic saline solution was injected, peculiar changes were not observed as composed with the rats without drug treatments. Pilocarpine injection produced structural changes suggestive of hyperfunction of the choroid cells. Their nuclei were oval in shape and the cytoplasmic organelles were extensively well-developed. Moreover, these cells possessed polypoidal microvilli with remakably expanded tips. On the other hand, puromycin injection caused structural changes suggesting degeneration or hypofunction of the choroid cells. Their nuclei showed irregular contour and the organelles were also depressed. The microvilli tended to have slender finger-like profile. In conclusion, the polypoid border which has been know as a characteristic of the choroid epithelium is not artifact in preparations but may be probably concerned with hyperfunction of this tissue.

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詳細情報 詳細情報について

  • CRID
    1390282681322477824
  • NII論文ID
    130000890307
  • DOI
    10.2739/kurumemedj.24.1
  • ISSN
    18812090
    00235679
  • 本文言語コード
    en
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
    • OpenAIRE
  • 抄録ライセンスフラグ
    使用不可

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