Influence of Imaging Parameters on the Measurement of Apparent Diffusion Coefficient

DOI Web Site 6 Citations 27 References
  • Ozaki Masanori
    School of Allied Health Sciences, Kitasato University
  • Ogura Akio
    Department of Radiology, Kyoto City Hospital
  • Muro Isao
    Department of Radiology, Tokai University Hospital
  • Miyati Tosiaki
    Division of Health Sciences, Kanazawa University Graduate School of Medical Science
  • Tamura Takayuki
    Department of Radiology, Hiroshima Atomic Bomb Casualty Council, Health Management & Promotion Center
  • Takahashi Mitsuyuki
    Department of Radiology, Federation of National Public Service and Affiliated Personnel Mutual Aid Associations, Yokohama Sakae Kyousai Hospital
  • Doi Tsukasa
    Department of Radiology, Osaka University Hospital
  • Tanji Hajime
    Imaging Center, Jinsenkai Medical Foundation, Northern Fukushima Medical Center
  • Takahashi Junji
    Department of Radiological Technology, Federation of National Public Service Personnel Mutual Aid Associations, Toranomon Hospital
  • Takizawa Osamu
    Siemens Asahi Medical Technologies Ltd. Marketing Division, R&C Group

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Other Title
  • 撮像パラメータがＡＤＣ測定に与える影響について
  • サツゾウ パラメータ ガ ADC ソクテイ ニ アタエル エイキョウ ニ ツイテ

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Abstract

The apparent diffusion coefficient (ADC) values are calculated by using signal intensity in diffusion-weighted images (DWIs) with two or more different b-value. Therefore, the signal to noise ratio (SNR) of DWI with higher b-value may have a big influence on the measured ADC value. We examined the influence of the imaging parameters on the calculated ADC values. The SNR of DWI increased by using a larger voxel size, by means of a decreased number of matrix, an increased slice thickness, and an increased field of view (FOV). However, when the number of excitations was increased to improve the SNR of DWI, the signal intensity of background noise was observed to be slightly increased. It was suggested that the consistency of measured ADC was not preserved when the signal of the DWIs with higher b-value dropped close to the noise level.

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