Experimental study on the effect of vitamin C long term loading on the serum LDH activity in man.

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  • Miyoshi Tamotsu
    Department of Public Health, School of medicine, The University of Tokushima
  • Imaki Masahide
    Department of Public Health, School of medicine, The University of Tokushima
  • Yoshimura Takeshi
    Department of Public Health, School of medicine, The University of Tokushima
  • Matsumoto Kazuoki
    Department of Public Health, School of medicine, The University of Tokushima

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Other Title
  • 人血清ＬＤＨ活性値に及ぼすビタミンＣ長期付加の影響に関する実験的研究
  • ヒトケッセイ LDH カッセイチ ニ オヨボス ビタミン C チョウキ フカ

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The effects of vitamin C intake on percentages of LDH-4 and LDH-5 fractions were examined in 5 healthy volunteers. The experiment lasted 43 months (usual diets; 12 months, usual diets+vitamin C 1g/day; 24 months, usual diets; 7 months). The variations of the percentages of LDH-4 and LDH-5 fractions were measuerd.<br>The results obtained were as follows.:<br>The percentage of LDH-4 in all subjects decreased with vitamin C adminstration, and decreased significantly (p<0.05) from 8.3±0.98% to 6.9±0.75% after 24 months.<br>The percentage of LDH-5 in all subjects decreased after vitamin C administration, and decreased significantly (p<0.05) from 9.4±4.9% to 8.0±3.95% after 24 months.<br>It is possible to conclude from the results that the percentages of the LDH-4 and LDH-5 fractions were affected by long-term vitamin C loading.

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