Examination of Visual Effect in Low-dose Cerebral CT Perfusion Phantom Image Using Iterative Reconstruction

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  • Ohmura Tomomi
    Department of Radiology, Research Institute for Brain and Blood Vessels-Akita Graduate School of Health Sciences, Niigata University
  • Lee Yongbum
    Graduate School of Health Sciences, Niigata University
  • Takahashi Noriyuki
    Department of Radiology, Research Institute for Brain and Blood Vessels-Akita
  • Sato Yuichiro
    Department of Radiology, Research Institute for Brain and Blood Vessels-Akita
  • Ishida Takato
    Department of Radiology, Research Institute for Brain and Blood Vessels-Akita
  • Toyoshima Hideto
    Department of Radiology, Research Institute for Brain and Blood Vessels-Akita

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Other Title
  • 画像再構成法の違いが低線量 CT perfusionの画質に及ぼす影響—模擬動態画像を用いた観察者実験—
  • 画像再構成法の違いが低線量CT perfusionの画質に及ぼす影響 : 模擬動態画像を用いた観察者実験
  • ガゾウ サイコウセイホウ ノ チガイ ガ テイセンリョウ CT perfusion ノ ガシツ ニ オヨボス エイキョウ : モギ ドウタイ ガゾウ オ モチイタ カンサツシャ ジッケン

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CT perfusion (CTP) is obtained cerebrovascular circulation image for assessment of stroke patients; however, at the expense of increased radiation dose by dynamic scan. Iterative reconstruction (IR) method is possible to decrease image noise, it has the potential to reduce radiation dose. The purpose of this study is to assess the visual effect of IR method by using a digital perfusion phantom. The digital perfusion phantom was created by reconstructed filtered back projection (FBP) method and IR method CT images that had five exposure doses. Various exposure dose cerebral blood flow (CBF) images were derived from deconvolution algorithm. Contrast-to-noise ratio (CNR) and visual assessment were compared among the various exposure dose and each reconstructions. Result of low exposure dose with IR method showed, compared with FBP method, high CNR in severe ischemic area, and visual assessment was significantly improvement. IR method is useful for improving image quality of low-dose CTP.

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