Novel Perfusion Evaluation Method Using Phase-ratio Image Map in Head 4D-CT
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- Ohmura Tomomi
- Department of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita Department of Radiological Technology, Graduate School of Health Sciences, Niigata University
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- Lee Yongbum
- Department of Radiological Technology, Graduate School of Health Sciences, Niigata University
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- Takahashi Noriyuki
- Department of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita
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- Toyoshima Hideto
- Department of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita
Bibliographic Information
- Other Title
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- 頭部4D-CT の位相比画像マップを用いた新たな灌流評価法
- トウブ 4D-CT ノ イソウヒ ガゾウ マップ オ モチイタ アラタ ナ カンリュウ ヒョウカホウ
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Abstract
<p>Purpose: CT perfusion (CTP) is a powerful tool for the assessment of cerebrovascular disease. However, CTP maps are significantly different depending on CTP software and algorithm, even when using identical image data. We developed a phase-ratio image map (PI map), which was a novel perfusion map, without using CTP software. The purpose of this study was to investigate the usefulness of the PI map by comparing it with a positron emission tomography (PET) image. Methods: Twenty patients (16 men, 4 women; mean age: 61.6 years) with unilateral cervical and intracranial steno-occlusive disease underwent CTP. CTP source images were obtained at 1-s intervals of 23 times and 5 intervals using dynamic multiphase imaging. An early-phase image was generated by computing the average of CT images for 5 s in the vicinity of the peak enhancement curve of a normal hemisphere. A delayed-phase image was generated by computing the average of CT images for 5 s immediately after the early phase. The PI map was created by dividing the delayed-phase image by the early-phase image. We investigated the validity of the PI map compared with PET-cerebral blood flow (CBF). Lesion-to-normal ratios between a PET-CBF and the PI map or two conventional CTP-CBFs were observed and compared, and the relative errors were also compared. Result: There was a strong correlation between the PET-CBF and the PI map (R=0.82). Correlations between the PET-CBF and two CTP-CBFs were weak (R=0.30) and middle (R=0.62), respectively. The relative error between the PI map and the PET-CBF was within 10% in most cases. Conclusion: The PI map was more similar to the PET-CBF on perfusion evaluation, and did not depend on CTP software. The robustness and simplicity of the PI mapping method would be advantageous compared with conventional CTP mapping methods.</p>
Journal
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- Japanese Journal of Radiological Technology
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Japanese Journal of Radiological Technology 73 (11), 1125-1131, 2017
Japanese Society of Radiological Technology
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Details 詳細情報について
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- CRID
- 1390282681367038976
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- NII Article ID
- 40021388866
- 130007330750
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- NII Book ID
- AN00197784
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- ISSN
- 18814883
- 03694305
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- NDL BIB ID
- 028670451
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- PubMed
- 29151545
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed