慢性肝疾患における血清リポたん白についての検討

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タイトル別名
  • STUDY OF SERUM LIPOPROTEINS IN PATIENTS WITH CHRONIC LIVER DISEASES

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Serum lipids, lipoprotein, plasma LCAT (lecithincholesterol acyltransferase) activity and liver function tests have been investigated in 171 out-patients with mild degree of various chronic liver diseases. Lipoprotein was measured by agarose-gel electrophoresis.<br>Alpha-lipoprotein was increased in most of patients, while beta-lipoprotein was decreased. Pre-beta-lipoprotein was markedly decreased in patients with cirrhosis of the liver. Preheta-lipoprotein was correlated positively to choline esterase, albumin and A/G ratio, and inversely to γ-globulin and ZTT. Decreased levels of pre-beta-lipoprotein was inversely correlated to plasma LCAT activity.<br>These results lead us to suggest that the electrophoretic patterns of lipoproteins may reflect the severity of chronic liver diseases.

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