A case of small cell carcinoma of the esophagus with remarkable response to chemotherapy with CPT-11 and CDDP

  • GOTO Toshihiro
    Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital
  • WATABE Hirotsugu
    Department of Gastroenterology, Tokyo University School of Medicine
  • KAWAKAMI Takayuki
    Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital
  • WATANABE Masashi
    Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital
  • NAKANO Kentaro
    Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital
  • TAKAI Atsuko
    Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital
  • KITAZAWA Eriko
    Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital
  • SATO Shinpei
    Department of Internal Medicine, Teikyo University Chiba Medical Center
  • TAJIMA Yasuo
    Department of Clinical Pathology, Teikyo University Mizonokuchi Hospital
  • MIZUGUCHI Kunio
    Department of Clinical Pathology, Teikyo University Mizonokuchi Hospital
  • KIKUCHI Kentaro
    Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital
  • MIYAKAWA Hiroshi
    Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital
  • MURAKAWA Yuji
    Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital

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Other Title
  • イリノテカンとシスプラチンの併用化学療法が著効した進行食道小細胞癌の1例

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Abstract

A 63-year-old man visited our hospital with complaints of the chest pain and loss of appetite. A computed tomography of chest showed wall thickening in the lower portion of the esophagus and carinal and para-aorta lymph node swelling. Upper gastrointestinal endoscopy revealed an irregular ulcerated lesion in the middle portion of the esophagus, which was pathologically diagnosed as small cell carcinoma. A computed tomography of the abdomen showed multiple liver metastases and para-aortic, cardiac, and common hepatic arterial lymph node swelling. One course of combined chemotherapy with CPT-11 and CDDP, then 3 courses of chemotherapy with CPT-11 showed clinical complete remission. <br>

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