日本人 (成人) の乳糖不耐症

DOI

書誌事項

タイトル別名
  • Intestinal Lactase Activity in Japanese Adults

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説明

Diarrhea with milk intake, that is milk intolerance, is not infrequently seen in Japanese adults. A large majority of milk intolerance is today considered as lactose intolerance.<br>Various clinical and animal experiments as listed below were carried out to study the pathogenesis of milk intolerance;<br>1) Questionaire of milk intolerance to general populations<br>2) Lactose tolerance test (LTT)<br>3) Light microscopic and electron microscopic study of human jejunal mucosa by biopsy<br>4) Assay of disaccharidase activity of the mucosa<br>5) Animal experiments with Wister rats-a) the change of intestinal disaccharidase activity after birth, b) lactose load feeding both in quantity and age differences, c) influence of lactase addition to the feed upon the diarrhea in lactose load feeding<br>6) Study of maximal blood sugar rise in LTT before and after milk loading in student nurses.<br>From all the above experiments the followings were concluded. In Japanese adults lactase activity in the jejunal mucosa is significantly low in comparison with that in the people of the U.S.A. and European countries. This low level of activity is mainly due to a low amount of lactose intake in their daily diet.

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詳細情報 詳細情報について

  • CRID
    1390282681378107392
  • NII論文ID
    130001070270
  • DOI
    10.11405/nisshoshi1964.68.37
  • ISSN
    13497693
    04466586
  • 本文言語コード
    en
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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