A case of Crohn's disease concomitant with IgA nephropathy

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  • ARAI Osamu
    Department of Gastroenterology, Hepatology and Nutrition, Kurashiki Medical Center
  • SHIBATA Norikuni
    Department of Gastroenterology, Hepatology and Nutrition, Kurashiki Medical Center
  • KUBOKI Makoto
    Department of Gastroenterology, Hepatology and Nutrition, Kurashiki Medical Center
  • IKEDA Hiroshi
    Department of Gastroenterology, Hepatology and Nutrition, Kurashiki Medical Center
  • OMOTO Kenji
    Department of Gastroenterology, Hepatology and Nutrition, Kurashiki Medical Center

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  • IgA腎症に合併したクローン病の1例

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Abstract

A 34-year-old woman with underlying IgA nephropathy was admitted to our hospital with chief complaints of abdominal pain and pyrexia. Computed tomography showed increased mural thickness of the ileum and increased mesenteric fat density. Colonoscopic findings revealed a longitudinal ulcer in the terminal ileum and irregularly shaped ulcers and a longitudinal ulcer scar in the descending colon. Histopathological analysis of biopsy specimens from the ileum and descending colon showed non-caseating epithelioid cell granuloma. On the basis of these findings, the condition of the patient was diagnosed as ileocolonic Crohn's disease, and the patient received parenteral nutrition, followed by elemental diet. The patient was responsive to nutrition therapy, and the amount of uric protein decreased as her Crohn's disease activity index decreased. In conclusion, we assume that the Crohn's disease activity correlated with that of IgA nephropathy.<br>

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