Enhancement of Intestinal IgA Production by Non-degassed Roasted Coffee Beans

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  • エージング処理をしていないコーヒー焙煎豆の腸管IgA産生増強効果
  • エージング ショリ オ シテ イナイ コーヒー バイセントウ ノ チョウカン IgA サンセイ ゾウキョウ コウカ

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Commercial roasted coffee beans are commonly degassed. However, we found that a large number of volatile compounds were lost from coffee extracts through this process. Extracts of non-degassed roasted coffee beans strongly enhanced intestinal IgA production in mice. Moreover, we found that 2-methylpyrazine, 2,5-dimethylpyrazine and 2,6-dimethylpyrazine, which were lost by degassing, enhanced intestinal IgA production in mice. These results indicate that if degassing is not carried out, or if degassing time is reduced, roasted coffee beans include sufficient volatile compounds to enhance intestinal IgA production in mice.

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