軽症高脂血症患者に及ぼすクロレラ錠剤摂取の影響

DOI Web Site 被引用文献4件 参考文献21件

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タイトル別名
  • Effect of Chlorella Tablet Ingestion on Mild Hypercholesterolemic Patients.
  • ケイショウ コウシケツショウ カンジャ ニ オヨボス クロレラ ジョウザイ セッシュ ノ エイキョウ

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Chlorella has long been considered to be a healthy food for hypercholesterolemic patients. However, its immediate effect on serum lipid levels has not yet been sufficiently elucidated clinically. We therefore evaluated the serum cholesterol lowering effect of Chlorella, cultured under heterotrophic conditions with glucose as a carbon source, in patients with mild hypercholeste-rolemia. Twenty patients with type IIa hypercholesterolemia were divided into two groups with similar clinical demographics. Eleven patients were each given 3g of Chlorella daily for 3 months (Chlorella group), while nine patients were not (Control group). In the Chlorella group, serum total cholesterol and LDL-cholesterol levels were significantly decreased. The Apo A-I level in serum was increased and atherogenic index (Apo B/Apo A-I) was decreased compared to that before Chlorella ingestion. Improvements in general physical conditions were also observed based on the results of a questionnaire survey. No appreciable side effects were seen during the study period. In the control group, no significant changes were observed during the study period in clinical findings except a temporary increase of the Apo B level in serum. These results indicate that daily ingestion of Chlorella has the potential to lower serum total cholesterol, LDL-cholesterol and atherogenic index in patients with mild hypercholesterolemia.

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