Toxicity Study on a Marine Snail <i>Turbo Argyrostoma</i>-III

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  • チョウセンサザエの有毒成分-III
  • チョウセンサザエの有毒成分III. : Candicineの分離同定
  • チョウセンサザエ ノ ユウドク セイブン 3 Candicine ノ ブンリ ドウテイ エイブン
  • Occurrence of Candicine
  • Candicineの分離同定

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Previous work on the viscera of a marine snail Turbo argyrostoma has revealed the presence of (3-methylthiopropyl) trimethylammonium chloride and an unidentified quaternary amine containing sulfur. In the present study, the occurrence of another amine having similar pharmacological activity was recognized. This third amine differed from the previous two in lacking sulfur and having a phenolic moiety. It was isolated by silicic acid column chromatography and was identified by chemical and spectral analyses as candicine chloride [(p-hydroxyphenethyl) trimethylammonium chloride].

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