Role of T cells in feline infectious peritonitis virus infection of suckling mice.

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  • 乳のみマウスのネコ伝染性腹膜炎(FIP)ウイルス感染におけるT細胞の役割
  • 乳のみマウスのネコ伝染性腹膜炎(FIP)ウイルス感染におけるT細胞の役割(短報)〔英文〕
  • チノミ マウス ノ ネコ デンセンセイ フクマクエン FIP ウイルス カンセ

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Abstract

Suckling nude (nu/nu) and heterozygous (nu/+) mice of age 2 weeks were inoculated intracerebrally with feline infectious peritonitis virus. Mortality of nu/+ mice was significantly lower than that of nu/nu mice. The resistance of nu/+ sucklings was considerably affected by anti-Thy 1.2 serum treatment, and mortality of nu/nu mice was reduced by transfer of T cells from 2-week-old nu/+ mice. Serum antibody was not detected by immunofluorescence in animals of any group surviving at 10 days postinoculation.

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