Design of Biointerface Formed by the Biocompatible Polymer Films and Application to PDMS Microchip Electrophoresis

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  • Takai Madoka
    Department of Bioengineering, The University of Tokyo
  • Nii Kyosuke
    Department of Materials Engineering, The University of Tokyo

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Other Title
  • 生体適合性ポリマー膜によるバイオインターフェースの創製とPDMSマイクロチップ電気泳動への応用
  • セイタイ テキゴウセイ ポリマーマク ニ ヨル バイオインターフェース ノ ソウセイ ト PDMS マイクロチップ デンキ エイドウ エ ノ オウヨウ

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Abstract

We prepared the biocompatible phospholipid polymer, poly [2-methacryloyloxyethyl phosphorylcholine (MPC)-co-3-(methacryloyloxy)propyltris (trimethylsilyloxy) silane (MPTSSi)]: PMMSi for the surface modification in microchannel of PDMS bioanalytical devices. The protein adsorption was resisted and electro-osmotic flow (EOF) was reduced on the PMMSi coated PDMS surface. The repeatable precision on electrophoresis was obtained, so it is expected the PMMSi coated interface is suitable for micro-bioanlysis.

Journal

  • MEMBRANE

    MEMBRANE 37 (4), 189-194, 2012

    THE MEMBRANE SOCIETY OF JAPAN

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