C型ボツリヌス菌菌体と毒素との結合とその病原的役割

DOI 日本農学文献記事索引 Web Site Web Site PubMed 被引用文献1件

書誌事項

タイトル別名
  • Cell-bound toxin of Clostridium botulinum type C and its pathogenic significance.
  • C型ボツリヌス菌菌体と毒素との結合とその病原的役割〔英文〕
  • Cガタ ボツリヌスキン キンタイ ト

この論文をさがす

抄録

Strains of Clostridium botulinum type C were cultured in a laboratory medium at 30, 37 and 42°C and their turbidities and cell and spore populations were measured periodically. They were grouped into four on the basis of the temperature giving the highest turbidity. When the turbidity was high, the toxic potency of culture supernatant was rather low and a larger portion of the toxin was released upon sonic disintegration of the bacterial cells. The cell-associated toxin was found to be orally more toxic to the chicken than the cell-free toxin. Type C-L toxin (Mr about 500 k) released by sonic disintegration of the cells rebound to the cells at pH2, whereas M toxin (Mr about 300 k) did not. Heat-treatment of the cells for 15 min at 80°C did not affect the binding. Type C toxin bound to the bacterial cells via a heat-stable cell component may play an important role in pathogenesis of chicken botulism.

収録刊行物

被引用文献 (1)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ