Development of a New Blood Purifing System Using Antithrombogenic Materials.

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Other Title
  • 抗血栓材料を用いた血液浄化システムの開発
  • コウ ケッセン ザイリョウ オ モチイタ ケツエキ ジョウカ システム ノ カ

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Description

By combining a polyacrylonitrile (PAN) -polyethyleneoxide (PEO) membrane with ionically heparin-bound catheter, tubing, and module header, a totally antithrombogenic continuous ultrafiltration system (ACUS) was developed. Antithrombogenicity of PAN-PEO hollow fiber membrane was considered to be due to the presence of highly concentrated PEO near the inner surface of the membrane wich has a finely dispersed microstructure. ACUS was clinically applied to 24 patients without systemic anticoagulation and one PAN-PEO filter functioned for average 32 hrs without deteriorating their bleeding tendencies.

Journal

  • MEMBRANE

    MEMBRANE 19 (6), 376-381, 1994

    THE MEMBRANE SOCIETY OF JAPAN

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