Quantitative Changes in Serum Concentration of Bovine Gut Chitinase in Theileria Infection
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- FUJIMOTO Wakako
- Laboratory of Histology and Cytology, Graduate School of Medicine, Hokkaido University
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- KIMURA Kazuhiro
- Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University
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- SUZUKI Masako
- Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
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- SYUTO Bunei
- Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
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- ONUMA Misao
- Laboratory of Infectious Disease, Graduate School of Veterinary Medicine, Hokkaido University
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- IWANAGA Toshihiko
- Laboratory of Histology and Cytology, Graduate School of Medicine, Hokkaido University
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抄録
Bovine gut chitinase is exclusively produced in the liver and secreted into the blood. In the present study, we established a semi-quantitative method by Western blot analysis for measurement of the chitinase content in blood and examined its alteration during postnatal development and experimental infection with hemoprotozoan parasite in cattle. Its serum levels from 1 week to 1 year of age showed a significant increase only in 3-4-month-old group. The plasma concentration of the gut chitinase was not changed during acute inflammation caused by lipopolysaccharide but increased gradually after a Theileria injection and peaked at 52 days post-infection. It appears that the increase in the blood chitinase levels might be a defensive response in cattle against protozoan infection.<br>
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 66 (3), 291-294, 2004
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390282681402572288
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- NII論文ID
- 130000448617
- 110003886397
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- NII書誌ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 6901775
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- PubMed
- 15107559
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可