Separate Development of Nitric Oxide Synthase- and Vasoactive Intestinal Polypeptide-Immunoreactive Nerves Arising from the Vertebral Artery in the Rat
-
- ANDO Koichi
- Biological Laboratory, Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kyushu Sangyo University
-
- YOSHIDA Souta
- Biological Laboratory, Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kyushu Sangyo University
-
- YAMAUCHI Hitoshi
- Biological Laboratory, Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kyushu Sangyo University
-
- KUBO Shinji
- Biological Laboratory, Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kyushu Sangyo University
-
- KUSABA Haruo
- Muromi Animal Hospital
Bibliographic Information
- Other Title
-
- ラット椎骨動脈経由の一酸化窒素合成酵素(NOS)および血管作用性腸管ペプチド(VIP)陽性神経による独自の発達様相
Search this article
Abstract
Development of nitric oxide synthase (NOS)-and vasoactive intestinal polypeptide (VIP)-immunoreactive (-IR) nerves supplying the basilar and vertebral arteries (BA and VA) was investigated in White Wistar rats, using double immunohistochemistry. NOS-IR and VIP-IR nerves via the anterior circulation (AC), which mostly expressed NO+/VIP+, extended to the BA during the second postnatal week, and usually reached as far as the rostral two third of the BA on PND 20. NOS-IR nerves were completely lack in the cBA and the VA on PND10, and often absent from these arterial regions even at PND 20. Nevertheless, a small number of VIP+/NOS- nerves were localized in the walls from the caudal BA (cBA) to the VA on PND 5. On PND 20, they frequently met with the descending NOS-IR and VIP-IR nerves via the AC around the lower portion of the middle BA. Fiber bundles containing NOS+/VIP+ axons were first visualized on the caudal VA at PND 30 and observed frequently at PND 80, with a distinct increase in number of NOS-IR and VIP-IR nerves supplying the cBA and the VA. Thus, NOS-IR nerves coming from the VA develop through its own characteristic sequence that lags markedly behind the time of appearance for VIP-IR nerves from the same vascular route and for NOS-IR and VIP-IR nerves via the AC.<br>
Journal
-
- Journal of Veterinary Medical Science
-
Journal of Veterinary Medical Science 68 (2), 125-130, 2006
JAPANESE SOCIETY OF VETERINARY SCIENCE
- Tweet
Details 詳細情報について
-
- CRID
- 1390282681402623104
-
- NII Article ID
- 110004675709
- 130000447997
-
- NII Book ID
- AA10796138
-
- ISSN
- 13477439
- 09167250
-
- NDL BIB ID
- 7851494
-
- Text Lang
- en
-
- Data Source
-
- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed