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Increase in Oxidized Proteins in Theileria sergenti-Infected Erythrocyte Membrane.
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- YAGI Yukio
- Hokkaido Research Station, National Institute of Animal Health
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- THONGNOON Prasobporn
- Southern Veterinary Research and Diagnosis Center
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- SHIONO Hiroki
- Hokkaido Research Station, National Institute of Animal Health
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- CHIKAYAMA Yukio
- Hokkaido Research Station, National Institute of Animal Health
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Description
As a part of the elucidation of the pathogenesis of anemia in Theileria sergenti infection, oxidized-erythrocyte membrane proteins (OEMPs) collected from T. sergenti-infected calves were examined. The amount of OEMPs were seen to increase with the progress of the anemia and showed a maximum value around the crisis period of the infection. The increase of OEMPs coincided with band Nos. 1, 2, 2.1, 3, 4.1, 5, 6, and 7. The majority of them was located at the Triton X-100 un-extractive phase, and was confirmed as cytoskeletal proteins. This evidence indicates the enhancement of erythrocytic oxidation, and suggests that it might be one of the aggravating factors of anemia in T. sergenti infection.
Journal
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- Journal of Veterinary Medical Science
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Journal of Veterinary Medical Science 64 (7), 623-625, 2002
JAPANESE SOCIETY OF VETERINARY SCIENCE
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Details 詳細情報について
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- CRID
- 1390282681402669056
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- NII Article ID
- 110003920927
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- NII Book ID
- AA10796138
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- COI
- 1:CAS:528:DC%2BD38Xmslyqtb4%3D
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- ISSN
- 13477439
- 09167250
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- NDL BIB ID
- 6231131
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- PubMed
- 12185319
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- NDL Search
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed