筋胃びらん由来鶏アデノウイルスの免疫抑制鶏に対する病原性

DOI 日本農学文献記事索引 Web Site Web Site PubMed 被引用文献5件 参考文献25件
  • MUROGA Norihiko
    Laboratory of Veterinary Microbiology, Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University
  • TAHARAGUCHI Satoshi
    Laboratory of Veterinary Microbiology, Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University
  • OHTA Hideyuki
    The Chemo-Sero-Therapeutic Research Institute
  • YAMAZAKI Ken-ichi
    The Chemo-Sero-Therapeutic Research Institute
  • TAKASE Kozo
    Laboratory of Veterinary Microbiology, Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University

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タイトル別名
  • Pathogenicity of Fowl Adenovirus Isolated from Gizzard Erosions to Immuno-Suppressed Chickens

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Pathogenicity of a fowl adenovirus (FAV), JM1/1 strain of serotype 1 derived from gizzard erosions of a broiler chicken, was examined to specific pathogen-free (SPF) chickens pre-treated with infectious bursal disease viruses (IBDVs) or cyclophosphamide (CY). Virulent IBDVs, classical type, were inoculated orally at 3 days of age of SPF chickens. CY was treated subcutaniously for 3 days after hatch. FAV was given orally at 30 days of age. At 40 days of age, all chickens were bled and autopsied for serology and gross observation. Gizzard lesions were ranked by the scores depending on their severities. IBDV- or CY-treated chickens showed significantly higher gizzard lesion scores than non treated birds. There were no gross lesions in any other organs except for bursal atrophy. Serologically, antibody production against FAV was highly suppressed by IBDV infection or CY treatment.<br>

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