Genetic and Antigenic Analyses of Bovine Respiratory Syncytial Virus Detected in Japan
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- YAEGASHI Gakuji
- Iwate Prefecture Central Livestock Hygiene Service Center
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- SEIMIYA Yukio M.
- Iwate Prefecture Central Livestock Hygiene Service Center
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- SEKI Yoshihisa
- Iwate Prefecture Central Livestock Hygiene Service Center
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- TSUNEMITSU Hiroshi
- Shichinohe Research Unit, National Institute of Animal Health
Bibliographic Information
- Other Title
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- 日本で検出された牛RSウイルスの分子学的および抗原学的解析
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Abstract
Genetic and antigenic analyses of bovine respiratory syncytial virus were conducted on 12 field strains from Tohoku and Hokuriku districts in Japan during from 2002 to 2004. On the phylogenetic tree of the nucleotide sequences of the glycoprotein region, the examined strains fell in the same cluster as the strain isolated in Nebraska and were classified as the subgroup III. The examined strains were subdivided into 2 lineages (A, B). Isoleucine 200 of the epitope domain was replaced by threonine as a feature of the lineage B strains. The examined strains showed the nucleotide sequence homologies of 88.3-93.3% with the known Japanese strains classified as the subgroup II and of 86.1-96.6% with those in the subgroup III. No significant difference was found on the neutralization index between the examined strain and the 52-163-13 phylogenetically similar to the Japanese vaccine one. The results suggest that the subgroup III strains have existed in Japan and that epidemics of the strains could be protected due to the present vaccination.<br>
Journal
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- Journal of Veterinary Medical Science
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Journal of Veterinary Medical Science 67 (2), 145-150, 2005
JAPANESE SOCIETY OF VETERINARY SCIENCE
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Keywords
Details 詳細情報について
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- CRID
- 1390282681403582080
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- NII Article ID
- 110003963693
- 130000448366
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- NII Book ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- NDL BIB ID
- 7260976
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- PubMed
- 15750309
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- Text Lang
- en
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed