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Antagonistic Effects of Atipamezole on Medetomidine-Induced Sedation in Horses
Bibliographic Information
- Other Title
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- ウマにおけるメデトミジンに対するアチパメゾールの拮抗効果(短報)
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Description
The antagonistic effects of atipamezole (20, 40, 60, 80, and 100μg/kg IV) on medetomidine (10 μg/kg IV)-induced sedation were evaluated in horses. Although 20 and 40μg/kg of atipamezole were not sufficient to reverse the sedation, 60μg/kg did effectively reverse the sedation. Atipamezole at 80μg/kg was more potent, and significantly shortened the duration of sedation without any apparent side effects, but a higher dose of 100μg/kg was not more effective than 80μg/kg. The possible use of atipamezole as a reversal agent may enhance the value and availability of medetomidine as a chemical restraint agent in horses.
Journal
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- Journal of Veterinary Medical Science
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Journal of Veterinary Medical Science 58 (10), 1049-1052, 1996
JAPANESE SOCIETY OF VETERINARY SCIENCE
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Keywords
Details 詳細情報について
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- CRID
- 1390282681403646720
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- NII Article ID
- 130003572289
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- COI
- 1:CAS:528:DyaK28XmvFWgsLk%3D
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- ISSN
- 13477439
- 09167250
- http://id.crossref.org/issn/09167250
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- PubMed
- 8916013
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed