An Immunohistochemical Study of Protein Kinase C in the Bovine Retina

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  • SHIN Taekyun
    Department of Veterinary Medicine, Graduate School, Cheju National University
  • KIM Seungjoon
    Department of Veterinary Medicine, Graduate School, Cheju National University
  • AHN Meejung
    Department of Veterinary Medicine, Graduate School, Cheju National University
  • KIM Heechul
    Department of Veterinary Medicine, Graduate School, Cheju National University

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  • Immunohistochemical Study of Protein Kinase C in the Bovine Retina

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Abstract

The expression of protein kinase C (PKC) was studied in the bovine retina by immunohistochemical analysis. Western blot analysis showed that PKC isoforms, including α, βI, δ and θ, were detected in the bovine retina. By immunohistochemistry, both PKC α and βI were expressed in all retinal layers, with an intense localization of both PKC α and βI detected in bipolar cells in the inner nuclear cell layer and in some glial cells in ganglion cell layers. The immunoreactivity of both PKC δ and θ was quite weak in the retinal layers, compared with that of PKC α and βI. These findings suggest that both conventional and novel PKCs are differentially expressed in the bovine retina.<br>

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